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Clinical Scholar Research Award

The Clinical Scholar Research Award was created to further the understanding of anesthesiology and related sciences in clinical practice through clinical investigations. After awarding almost $5 million to 62 recipients from 1994 until 2011, this award became the IARS Mentored Research Award.

Past Recipients

Wilton A. van Klei, MD, PhD
Effect of routine postoperative troponin measurements on one year cardiac events and death
University Medical Center Utrecht
Utrecht, Netherlands
Jennifer K. Lee, MD
Non-invasively monitoring cerebrovascular autoregulation after pediatric cardiac arrest
Johns Hopkins University School of Medicine
Baltimore, Maryland

 

Patrick Meybohm, MD
Remote ischemic preconditioning for congenital heart surgery (RIP CoHeart-Study)
University Hospital Schleswig-Holstein
Kiel, Germany

 

Jacob Raphael, MD
Haptoglobin polymorphism as a predictor of major adverse cardiac events and acute kidney injury after coronary artery bypass surgery in patients with diabetes
University of Virginia
Charlottesville, Virginia

 

Wyndam M. Strodtbeck, MD
Differential tolerance to opioid-mediated analgesia and respiratory depression in subjects chronically taking opioids
Virginia Mason Medical Center
Seattle, Washington

Roisin Ni Mhuircheartaigh, MB, BCh (Hons) MRCPI, FFARCSI
The “thalamocortical switch” and consciousness; is interruption of thalamocortical transmission the cause or a consequence of induction of general anaesthesia by propofol
University of Oxford
Oxford, United Kingdom

Tjorvi E. Perry, MD
Genetic influences on complement activation and perioperative myocardial injury following coronary artery
bypass graft surgery

Brigham and Women’s Hospital
Boston, Massachusetts

Leonie Lang Siegel, MD
Differentiating peripherally from centrally mediated opioid analgesia in postoperative pain
University Hospital Benjamin Franklin
Berlin, Germany

Greg Stratmann, MD, PhD
Is pediatric anesthesia associated with long-term hippocampal dysfunction?
University of California, San Francisco
San Francisco, California

Ralph Joachim Fuchs, MD, PhD
Determining the Role of Nrf2 and Disrupted Iron Homeostasis in Innate Immune Response and Survival during Septic Shock in Critically Ill Adults
Johns Hopkins University School of Medicine
Baltimore, Maryland

Konrad Meissner, MD
Role of P-glycoprotein in Cerebral Morphine Disposition and Analgesia
Washington University
St. Louis, Missouri

B. (Benedikt) Preckel, MD, DEAA
Organ Protection by Noble Gases-Helium Induced Early and Late Preconditioning in Human Endothelium
University of Amsterdam
Amsterdam, Netherlands

Rene Schmidt, MD
Organ Protection by Hepatic Heme Oxygenase-1 Up-Regulation Through Volatile Anesthetics in Humans
University Medical Center Freiburg
Freiburg, Germany

Klaus Hahnenkamp, MD
Perioperative protective effects of lidocaine – Clinical study on the route and timing of administration
University Hospital
Muenster, Germany

Kerstin Jurk, MD
Role of platelets of inflammatory modulators in the pathogenesis of sepsis
University Hospital
Muenster, Germany

Claus Niemann, MD
Ischemia reperfusion injury during total knee athroplasty: The impact of metabolic syndrome
University of California, San Francisco
San Francisco, California

Bernhard Riedel, MB, ChB, FCA, MMed, FAHA, PhD
Perioperative endothelial kinetics – A predictor of outcome following major surgery
University of Texas MD Anderson Cancer Center
Houston, Texas

Madhav Swaminathan, MD
The role of circulating progenitor cells in renal outcomes after cardiac valve surgery
Duke University
Durham, North Carolina

Lisa Wise-Faberowski, MD
Neurological outcomes in infants with congenital heart defects: The effect of anesthestic agents
University of Colorado Health Sciences Center
Aurora, Colorado

Giora Landesberg, MD, DSc, MBA
Cardiac morbidity and mortality in high-risk general ICU patients: Pathophysiology and prospective randomized trial
Hebrew University – Hadassah Medical Center
Jerusalem, Israel

Kyle T.S. Pattinson, BM, FRCA
Investigation of pharmacological modulation of respiratory control using fMRI
University of Oxford
Oxford, United Kingdom

Esther M. Pogatzki-Zahn, MD, PhD
The role of the menstrual cycle, sex hormones and gender for modulation of pain perception and cortical activation after an experimental incision in human volunteers
University Hospital
Muenster, Germany

Sam R. Sharar, MD
Subjective and neuroimaging assessment of combined opioid and virtual reality analgesia
University of Washington
Seattle, Washington

Ruth Zaslansky, DSc
Topical morphine for analgesia and promotion of wound healing in patients with skin-graft donor sites
Charité-Universitatsmedizin Berlin
Berlin, Germany

David M. Ansley, MD
Propofol cardioprotection for Type II diabetes
University of British Columbia
Vancouver, British Columbia, Canada

Anthony M. Roche, MBChB, FRCA, MMed
Tissue factor mediated perioperative hypercoagulability – The role of lipopolysaccharide
Duke University
Durham, North Carolina

Tracy Stierer, MD
Early identification of sleep apnea
Johns Hopkins University School of Medicine
Baltimore, Maryland

Christer Svensén, MD, PhD, DEAA, MBA
Potent inhalation of anesthetic agents extravascular accumulation of infused fluids in humans
University of Texas Medical Branch at Galveston
Galveston, Texas

Pamela Flood, MD
Hyperalgesic effects of volatile anesthetics in postoperative patients: Prevention with nicotine
Columbia University
New York, New York

John Robinson Keltner, MD, PhD
Brain circuitry underlying anticipation of pain and placebo analgesia – An fMRI study
University of California, San Francisco
San Francisco, California

Diederik van Dijk, MD, PhD, MPH
Long-term cognitive decline after coronary artery bypass grafting: Is off-pump surgery beneficial?
University Medical Center Utrecht
Utrecht, Netherlands

Cynthia A. Wong, MD
Neuraxial vs. systemic analgesia for latent phase labor analgesia in nulliparous parturients with induction of labor: Effect on rate of operative delivery
Northwestern University
Evanston, Illinois

Shahbaz R. Arain, MD
Autonomic and vascular effects of anesthetics in humans
Medical College of Wisconsin
Milwaukee, Wisconsin

Yehuda Ginosar, BSc, MBBS
Antepartum chronic epidural therapy (ACET) for pre-eclampsia and intrauterine growth retardation: Dose findings study and randomized clinical trial
Hebrew University – Hadassah Medical Center
Jerusalem, Israel

Steven E. Kern, PhD
Assessing the interaction of morphine and its metabolites in human volunteers
University of Utah
Salt Lake City, Utah

Arthur J. Cronin, MD
Perioperative melatonin replacement to preserve postoperative circadian rhythm
Penn State/Milton S. Hershey Medical Center
University Park, Pennsylvania

Holly A. Muir, MD
B2-Adrenergic receptor genetic polymorphisms: Effect on uterine quiescence and preterm delivery
Duke University
Durham, North Carolina

J. Russell Norton, MD
The effects and interaction of sedative doses of intraveneous midazolam or propofol and hypoxia on upper airway obstruction
University of Rochester
Rochester, New York

Yaakov Beilin, MD
The effect of epidural fentanyl on infant breastfeeding: A prospective randomized study
Mount Sinai School of Medicine
New York, New York

Thomas Schricker, MD, PhD
Understanding how epidural analgesia attenuates postoperative protein catabolism: Modulation of substrate utilization and tissue insulin sensitivity
McGill University
Montreal, Quebec, Canada

Brian A. Williams, MD, MBA
Outcomes after anterior cruciate ligament reconstruction: effect of femoral nerve block analgesia
University of Pittsburgh
Pittsburgh, Pennsylvania

Miodrag Filipovic, MD
The effect of sevoflurane and propofol on the diastolic function of the left ventricle: An echocardiographic in vivo study
Kantonsspital Basel University Hospital
Basel, Switzerland

Lee A. Fleisher, MD
Perioperative anemia recovery from surgery trial (PARST)
Johns Hopkins University School of Medicine
Baltimore, Maryland

Ferenc E. Gyulai, MD
Anesthetic mechanisms by in vivo human imaging
University of Pittsburgh
Pittsburgh, Pennsylvania

Pierre Fiset, MD
Cholinergic mechanisms mediating loss of consciousness produced by anesthetic drugs in healthy human volunteers
McGill University
Montreal, Quebec, Canada

Tong Joo Gan, MD, BS, FRCA
Enhancing recovery outcomes in elderly ambulatory patients
Duke University
Durham, North Carolina

Christopher K. McQuitty, MD
Effect of single-dose glucocorticosteroids and aprotinin on b-andrenrgic receptor dysfunction and cytokine generation after cardiopulmonary bypass
University of Texas Medical Branch at Galveston
Galveston, Texas

David Amar, MD
Atrial fibrillation following thoracic surgery: Role of calcium channel activation
Memorial Sloan-Kettering Cancer Center
New York, New York

Paul B. Langevin, MD
Vascular responsiveness in pregnancy and pre-eclampsia
University of Florida
Gainesville, Florida

Chun-Su Yuan, MD, PhD
Antagonism of opioid-induced gut effects
University of Chicago
Chicago, Illinois

Robert H. Brown, MD, MPH
Mechanisms of stretch relaxation in normal and asthmatic human airways measured by High Resolution Computed Tomography (HRCT)
Johns Hopkins University School of Medicine
Baltimore, Maryland

Jeffrey K. Lu, MD
The effect of intrathecal morphine on the ventilatory response to hypoxia
University of Utah
Salt Lake City, Utah

Lena S. Sun, MD
Adrenoceptor function in the immature human myocardium
Columbia University
New York, New York

Steven M. Frank, MD
Determinates of the adrenergic and metabolic responses to core hypothermia
Johns Hopkins University School of Medicine
Baltimore, Maryland

Mark S. Wallace, MD
Neurosensory findings after intraveneous lidocaine in healthy volunteers and neuropathic pain states
University of California, San Diego
San Diego, California

William L. Young, MD
Pharmacological manipulation of cerebrovascular resistance to treat cerebral ischemia
Columbia University
New York, New York

Leonard Firestone, MD
Central loci and mechanisms of analgesia; Elucidation by positron emission tomography
University of Pittsburgh
Pittsburgh, Pennsylvania

David D. Hood, MD
Intrathecal neostigmine methylsulfate: A novel approach to spinal analgesia
Wake Forest University Medical Center
Winston-Salem, North Carolina

Manfred Seeberger, MD
Intraoperative transesophageal dobutamine stress echocardiography for perioperative risk assessment in patients with an increases risk of ischemia cardiac events
University of Basel
Basel, Switzerland

Isobel A. Muhiudeen, MD, PhD
Effects of inhaled nitric oxide on pulmonary hypertension in infants and children undergoing surgical repair of congenital heart disease
University of California, San Francisco
San Francisco, California

Robert E. Shangraw, MD, PhD
Effect of dichloroacetate on core-cycle metabolism, acid-base stability, and graft function in liver transplantation patients
Oregon Health and Science University
Portland, Oregon

Richard Smiley, MD, PhD
Beta-Adrenergic receptor regulation during pregnancy
Columbia University
New York, New York

2011
Wilton A. van Klei, MD, PhD
Effect of routine postoperative troponin measurements on one year cardiac events and death
University Medical Center Utrecht
Utrecht, Netherlands
2010
Jennifer K. Lee, MD
Non-invasively monitoring cerebrovascular autoregulation after pediatric cardiac arrest
Johns Hopkins University School of Medicine
Baltimore, Maryland

 

Patrick Meybohm, MD
Remote ischemic preconditioning for congenital heart surgery (RIP CoHeart-Study)
University Hospital Schleswig-Holstein
Kiel, Germany

 

Jacob Raphael, MD
Haptoglobin polymorphism as a predictor of major adverse cardiac events and acute kidney injury after coronary artery bypass surgery in patients with diabetes
University of Virginia
Charlottesville, Virginia

 

Wyndam M. Strodtbeck, MD
Differential tolerance to opioid-mediated analgesia and respiratory depression in subjects chronically taking opioids
Virginia Mason Medical Center
Seattle, Washington

2009

Roisin Ni Mhuircheartaigh, MB, BCh (Hons) MRCPI, FFARCSI
The “thalamocortical switch” and consciousness; is interruption of thalamocortical transmission the cause or a consequence of induction of general anaesthesia by propofol
University of Oxford
Oxford, United Kingdom

Tjorvi E. Perry, MD
Genetic influences on complement activation and perioperative myocardial injury following coronary artery
bypass graft surgery

Brigham and Women’s Hospital
Boston, Massachusetts

Leonie Lang Siegel, MD
Differentiating peripherally from centrally mediated opioid analgesia in postoperative pain
University Hospital Benjamin Franklin
Berlin, Germany

Greg Stratmann, MD, PhD
Is pediatric anesthesia associated with long-term hippocampal dysfunction?
University of California, San Francisco
San Francisco, California

2008

Ralph Joachim Fuchs, MD, PhD
Determining the Role of Nrf2 and Disrupted Iron Homeostasis in Innate Immune Response and Survival during Septic Shock in Critically Ill Adults
Johns Hopkins University School of Medicine
Baltimore, Maryland

Konrad Meissner, MD
Role of P-glycoprotein in Cerebral Morphine Disposition and Analgesia
Washington University
St. Louis, Missouri

B. (Benedikt) Preckel, MD, DEAA
Organ Protection by Noble Gases-Helium Induced Early and Late Preconditioning in Human Endothelium
University of Amsterdam
Amsterdam, Netherlands

Rene Schmidt, MD
Organ Protection by Hepatic Heme Oxygenase-1 Up-Regulation Through Volatile Anesthetics in Humans
University Medical Center Freiburg
Freiburg, Germany

2007

Klaus Hahnenkamp, MD
Perioperative protective effects of lidocaine – Clinical study on the route and timing of administration
University Hospital
Muenster, Germany

Kerstin Jurk, MD
Role of platelets of inflammatory modulators in the pathogenesis of sepsis
University Hospital
Muenster, Germany

Claus Niemann, MD
Ischemia reperfusion injury during total knee athroplasty: The impact of metabolic syndrome
University of California, San Francisco
San Francisco, California

Bernhard Riedel, MB, ChB, FCA, MMed, FAHA, PhD
Perioperative endothelial kinetics – A predictor of outcome following major surgery
University of Texas MD Anderson Cancer Center
Houston, Texas

Madhav Swaminathan, MD
The role of circulating progenitor cells in renal outcomes after cardiac valve surgery
Duke University
Durham, North Carolina

Lisa Wise-Faberowski, MD
Neurological outcomes in infants with congenital heart defects: The effect of anesthestic agents
University of Colorado Health Sciences Center
Aurora, Colorado

2006

Giora Landesberg, MD, DSc, MBA
Cardiac morbidity and mortality in high-risk general ICU patients: Pathophysiology and prospective randomized trial
Hebrew University – Hadassah Medical Center
Jerusalem, Israel

Kyle T.S. Pattinson, BM, FRCA
Investigation of pharmacological modulation of respiratory control using fMRI
University of Oxford
Oxford, United Kingdom

Esther M. Pogatzki-Zahn, MD, PhD
The role of the menstrual cycle, sex hormones and gender for modulation of pain perception and cortical activation after an experimental incision in human volunteers
University Hospital
Muenster, Germany

Sam R. Sharar, MD
Subjective and neuroimaging assessment of combined opioid and virtual reality analgesia
University of Washington
Seattle, Washington

Ruth Zaslansky, DSc
Topical morphine for analgesia and promotion of wound healing in patients with skin-graft donor sites
Charité-Universitatsmedizin Berlin
Berlin, Germany

2005

David M. Ansley, MD
Propofol cardioprotection for Type II diabetes
University of British Columbia
Vancouver, British Columbia, Canada

Anthony M. Roche, MBChB, FRCA, MMed
Tissue factor mediated perioperative hypercoagulability – The role of lipopolysaccharide
Duke University
Durham, North Carolina

Tracy Stierer, MD
Early identification of sleep apnea
Johns Hopkins University School of Medicine
Baltimore, Maryland

Christer Svensén, MD, PhD, DEAA, MBA
Potent inhalation of anesthetic agents extravascular accumulation of infused fluids in humans
University of Texas Medical Branch at Galveston
Galveston, Texas

2004

Pamela Flood, MD
Hyperalgesic effects of volatile anesthetics in postoperative patients: Prevention with nicotine
Columbia University
New York, New York

John Robinson Keltner, MD, PhD
Brain circuitry underlying anticipation of pain and placebo analgesia – An fMRI study
University of California, San Francisco
San Francisco, California

Diederik van Dijk, MD, PhD, MPH
Long-term cognitive decline after coronary artery bypass grafting: Is off-pump surgery beneficial?
University Medical Center Utrecht
Utrecht, Netherlands

Cynthia A. Wong, MD
Neuraxial vs. systemic analgesia for latent phase labor analgesia in nulliparous parturients with induction of labor: Effect on rate of operative delivery
Northwestern University
Evanston, Illinois

2003

Shahbaz R. Arain, MD
Autonomic and vascular effects of anesthetics in humans
Medical College of Wisconsin
Milwaukee, Wisconsin

Yehuda Ginosar, BSc, MBBS
Antepartum chronic epidural therapy (ACET) for pre-eclampsia and intrauterine growth retardation: Dose findings study and randomized clinical trial
Hebrew University – Hadassah Medical Center
Jerusalem, Israel

Steven E. Kern, PhD
Assessing the interaction of morphine and its metabolites in human volunteers
University of Utah
Salt Lake City, Utah

2002

Arthur J. Cronin, MD
Perioperative melatonin replacement to preserve postoperative circadian rhythm
Penn State/Milton S. Hershey Medical Center
University Park, Pennsylvania

Holly A. Muir, MD
B2-Adrenergic receptor genetic polymorphisms: Effect on uterine quiescence and preterm delivery
Duke University
Durham, North Carolina

J. Russell Norton, MD
The effects and interaction of sedative doses of intraveneous midazolam or propofol and hypoxia on upper airway obstruction
University of Rochester
Rochester, New York

2001

Yaakov Beilin, MD
The effect of epidural fentanyl on infant breastfeeding: A prospective randomized study
Mount Sinai School of Medicine
New York, New York

Thomas Schricker, MD, PhD
Understanding how epidural analgesia attenuates postoperative protein catabolism: Modulation of substrate utilization and tissue insulin sensitivity
McGill University
Montreal, Quebec, Canada

Brian A. Williams, MD, MBA
Outcomes after anterior cruciate ligament reconstruction: effect of femoral nerve block analgesia
University of Pittsburgh
Pittsburgh, Pennsylvania

2000

Miodrag Filipovic, MD
The effect of sevoflurane and propofol on the diastolic function of the left ventricle: An echocardiographic in vivo study
Kantonsspital Basel University Hospital
Basel, Switzerland

Lee A. Fleisher, MD
Perioperative anemia recovery from surgery trial (PARST)
Johns Hopkins University School of Medicine
Baltimore, Maryland

Ferenc E. Gyulai, MD
Anesthetic mechanisms by in vivo human imaging
University of Pittsburgh
Pittsburgh, Pennsylvania

1999

Pierre Fiset, MD
Cholinergic mechanisms mediating loss of consciousness produced by anesthetic drugs in healthy human volunteers
McGill University
Montreal, Quebec, Canada

Tong Joo Gan, MD, BS, FRCA
Enhancing recovery outcomes in elderly ambulatory patients
Duke University
Durham, North Carolina

Christopher K. McQuitty, MD
Effect of single-dose glucocorticosteroids and aprotinin on b-andrenrgic receptor dysfunction and cytokine generation after cardiopulmonary bypass
University of Texas Medical Branch at Galveston
Galveston, Texas

1998

David Amar, MD
Atrial fibrillation following thoracic surgery: Role of calcium channel activation
Memorial Sloan-Kettering Cancer Center
New York, New York

Paul B. Langevin, MD
Vascular responsiveness in pregnancy and pre-eclampsia
University of Florida
Gainesville, Florida

Chun-Su Yuan, MD, PhD
Antagonism of opioid-induced gut effects
University of Chicago
Chicago, Illinois

1997

Robert H. Brown, MD, MPH
Mechanisms of stretch relaxation in normal and asthmatic human airways measured by High Resolution Computed Tomography (HRCT)
Johns Hopkins University School of Medicine
Baltimore, Maryland

Jeffrey K. Lu, MD
The effect of intrathecal morphine on the ventilatory response to hypoxia
University of Utah
Salt Lake City, Utah

Lena S. Sun, MD
Adrenoceptor function in the immature human myocardium
Columbia University
New York, New York

1996

Steven M. Frank, MD
Determinates of the adrenergic and metabolic responses to core hypothermia
Johns Hopkins University School of Medicine
Baltimore, Maryland

Mark S. Wallace, MD
Neurosensory findings after intraveneous lidocaine in healthy volunteers and neuropathic pain states
University of California, San Diego
San Diego, California

William L. Young, MD
Pharmacological manipulation of cerebrovascular resistance to treat cerebral ischemia
Columbia University
New York, New York

1995

Leonard Firestone, MD
Central loci and mechanisms of analgesia; Elucidation by positron emission tomography
University of Pittsburgh
Pittsburgh, Pennsylvania

David D. Hood, MD
Intrathecal neostigmine methylsulfate: A novel approach to spinal analgesia
Wake Forest University Medical Center
Winston-Salem, North Carolina

Manfred Seeberger, MD
Intraoperative transesophageal dobutamine stress echocardiography for perioperative risk assessment in patients with an increases risk of ischemia cardiac events
University of Basel
Basel, Switzerland

1994

Isobel A. Muhiudeen, MD, PhD
Effects of inhaled nitric oxide on pulmonary hypertension in infants and children undergoing surgical repair of congenital heart disease
University of California, San Francisco
San Francisco, California

Robert E. Shangraw, MD, PhD
Effect of dichloroacetate on core-cycle metabolism, acid-base stability, and graft function in liver transplantation patients
Oregon Health and Science University
Portland, Oregon

Richard Smiley, MD, PhD
Beta-Adrenergic receptor regulation during pregnancy
Columbia University
New York, New York