2008 Clinical Scholar Research Award

B. (Benedikt) Preckel, MD, DEAA
Professor of Anaesthesiology, specialising in Patient Safety during the perioperative process
Faculty of Medicine
University of Amsterdam
Amsterdam, Netherlands

Dr. Preckel’s Research

Organ Protection by Noble Gases-Helium Induced Early and Late Preconditioning in Human Endothelium.

Related Publications

Noble gases as cardio-protectants – translatability and mechanism.
Smit KF, Weber NC, Hollmann MW, Preckel B.

Several noble gases, although classified as inert substances, exert in different experimental models tissue protection when applied before organ ischaemia as an early or late preconditioning stimulus, after ischaemia as a postconditioning stimulus…

Reduction of cardiac cell death after helium postconditioning in rats: transcriptional analysis of cell death and survival pathways.
Oei GT, Heger M, Van Golen RF, Alles LK, Flick M, Van Der Wal AC, Van Gulik TM, Hollmann MW, Preckel B, Weber NC.

Helium, a noble gas, has been safely used in humans. In animal models of regional myocardial ischemia/reperfusion it was shown that helium conditioning reduces infarct size. Currently it is not known how helium exerts its cytoprotective effects and which cell death/survival pathways are affected…

Read Dr. Preckel’s recent publications and articles.

Encourage, stimulate, and fund ongoing anesthesia-related research projects that will enhance and advance the specialty, and to disseminate current, state-of-the-art, basic and clinical research data in all areas of clinical anesthesia, including perioperative medicine, critical care, and pain management. The IARS is focused solely on the advancement and support of education and scientific research related to anesthesiology.

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This award is intended to support investigations that will further the understanding of clinical practice in anesthesiology and related sciences. Up to four research projects are selected annually, with a maximum award of $175,000 each, payable over two years.

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