2009 Clinical Scholar Research Award
University Hospital Benjamin Franklin
Dr. Lang Siegel’s Research
Differentiating peripherally from centrally mediated opioid analgesia in postoperative pain.
Peripheral mechanisms of opioid analgesia.
Stein C, Lang LJ.
Potent and clinically significant analgesic effects can be brought about by opioids acting outside the central nervous system. Injury and inflammation of peripheral tissues leads to increased synthesis, axonal transport, membrane-directed trafficking and G-protein coupling of opioid receptors in dorsal root ganglion neurons…
Opioids in rheumatic diseases.
Lang LJ, Pierer M, Stein C, Baerwald C.
Opioids are the most potent analgesics available and are well established for the treatment of severe acute, surgical, and cancer pain. However, their use to ameliorate chronic noncancer pain (CNCP) is still controversial because of the side effects…
Read Dr. Lang Siegel’s recent publications and articles.