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Association of Time to Surgery After COVID-19 Infection With Risk of Postoperative Cardiovascular Morbidity. 12/14/2022. Bryant JM. JAMA Netw Open.

This retrospective study from Vanderbilt was conducted among 3997 adult patients with a history of COVID-19, who were undergoing surgery from January 2020 to December 2021. The primary outcome was the composite occurrence of DVT, PE, CVA , MI, acute kidney injury, and death within 30 days after surgery.
The median time from COVID-19 diagnosis to surgery was 98 days. Major postoperative cardiovascular events were identified in 12.1%. Increased time from COVID-19 diagnosis to surgery was associated with a decreased rate of the composite outcome (adjusted odds ratio, 0.99 [per 10 days]; 95% CI, 0.98-1.00; P_=_.006). This study suggests that increased time from COVID-19 diagnosis to surgery was associated with decreased odds of experiencing major postoperative cardiovascular morbidity.
SAB Comment: The data is from a prior COVID-19 variant and may not be relevant to current practice. The authors were not able to suggest a time when the procedures would be safer. The specifics of the procedures are not detailed limiting the applicability of these findings. The rate of decrease in the composite endpoint over time was noted to be quite slow. These data still suggest the individualized assessment for each patient with respect to the type of the procedure, anesthesia and their co-morbidities.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2799548 

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