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2009 SCA-IARS Starter Grant

Martina Nowak-Machen, MD

Department of Anesthesiology, Perioperative and Pain Medicine
Brigham and Women’s Hospital
Harvard Medical School
Boston, Massachusetts

Dr. Nowak-Machen’s Research

ACD39 modulates NKT cell-induced oxygen toxicity in the lung.

Related Publications

Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury.
Nowak-Machen M, Schmelzle M, Hanidziar D, Junger W, Exley M, Otterbein L, Wu Y, Csizmadia E, Doherty G, Sitkovsky M, Robson SC.

Critically ill patients are routinely exposed to high concentrations of supplemental oxygen for prolonged periods of time, which can be life-saving in the short term, but such exposure also causes severe lung injury and increases mortality. To address this therapeutic dilemma…

Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively: a case control study.
Nowak-Machen M, Rawn JD, Shekar PS, Mitani A, Tuli S, Bingold TM, Lawlor G, Eltzschig HK, Shernan SK, Rosenberger P.

Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-aortic balloon pump (IABP) support. Use of an IABP has been linked to an increased incidence of…

Read Dr. Nowak-Machen’s recent publications and articles.