2009 SCA-IARS Starter Grant
Brigham and Women’s Hospital
Harvard Medical School
Dr. Nowak-Machen’s Research
ACD39 modulates NKT cell-induced oxygen toxicity in the lung.
Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury.
Nowak-Machen M, Schmelzle M, Hanidziar D, Junger W, Exley M, Otterbein L, Wu Y, Csizmadia E, Doherty G, Sitkovsky M, Robson SC.
Critically ill patients are routinely exposed to high concentrations of supplemental oxygen for prolonged periods of time, which can be life-saving in the short term, but such exposure also causes severe lung injury and increases mortality. To address this therapeutic dilemma…
Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively: a case control study.
Nowak-Machen M, Rawn JD, Shekar PS, Mitani A, Tuli S, Bingold TM, Lawlor G, Eltzschig HK, Shernan SK, Rosenberger P.
Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-aortic balloon pump (IABP) support. Use of an IABP has been linked to an increased incidence of…
Read Dr. Nowak-Machen’s recent publications and articles.
The IARS contributes more than $1 million each year to fund important anesthesia research. Your donation will help support innovative and forward-thinking anesthesia research and education initiatives, all of which are designed to benefit patient care. You can feel good knowing that 100% of your donation is directly allocated to research.