2010 SCA-IARS Mid-Career Grant and 2007 SCA Starter Grant

Gregory M.T. Hare, MD, PhD, FRCPC

Professor, Departments of Anesthesia and Physiology
Associate Member, Institute of Medical Science
Scientist, Li Ka Shing Knowledge Institute
St. Michael’s Hospital
Keenan Research Centre
Toronto, Ontario, Canada

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Dr. Hare’s Research

2010 SCA-IARS Mid-Career Grant

Determining the hemoglobin threshold for hypoxic cellular responses: Studies in anemic hypoxia inducible factor (HIF)-ODD-luciferase mice.

2007 SCA-IARS Starter Grant

The Threshold Hematocrit for Cerebral Hypoxia is Maintained by Protective Cardiovascular Mechanisms: The Role for Neuronal Nitric Oxide Synthase (nNOS).

Dr. Hare has a clinical focus in blood conservation, as well as defining adaptive and maladaptive cerebral and cardiovascular regulatory mechanisms in experimental models of acute hemodilution.

Related Publications

Transfusion Triggers for Guiding RBC Transfusion for Cardiovascular Surgery: A Systematic Review and Meta-Analysis.
Curley GF, Shehata N, Mazer CD, Hare GM, Friedrich JO..

Restrictive red cell transfusion is recommended to minimize risk associated with exposure to allogeneic blood. However, perioperative anemia is an independent risk factor for adverse outcomes after cardiovascular surgery. The purpose of this systematic review and meta-analysis is to determine whether perioperative restrictive transfusion thresholds are associated with inferior clinical outcomes in randomized trials of cardiovascular surgery patients.

Anesthetic approach to high-risk patients and prolonged awake craniotomy using dexmedetomidine and scalp block.
Garavaglia MM1, Das S, Cusimano MD, Crescini C, Mazer CD, Hare GM, Rigamonti A.

Awake craniotomy with intraoperative speech or motor testing is relatively contraindicated in cases requiring prolonged operative times and in patients with severe medical comorbidities including anxiety, anticipated difficult airway, obesity, large tumors, and intracranial hypertension. The anesthetic management of neurosurgical patients who possess these contraindications but would be optimally treated by an awake procedure remains unclear.

Encourage, stimulate, and fund ongoing anesthesia-related research projects that will enhance and advance the specialty, and to disseminate current, state-of-the-art, basic and clinical research data in all areas of clinical anesthesia, including perioperative medicine, critical care, and pain management. The IARS is focused solely on the advancement and support of education and scientific research related to anesthesiology.
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2019 Annual Meeting

The 2019 IARS Annual Meeting and International Science Symposium will be aligned with the Society of Critical Care Anesthesiologists (SOCCA) and Association of University Anesthesiologists (AUA) Annual Meetings, May 16 – May 24, 2019 at the Fairmont The Queen Elizabeth Hotel in Montreal, Quebec, Canada.

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Support IARS

The IARS contributes more than $1 million each year to fund important anesthesia research. Your donation will help support innovative and forward-thinking anesthesia research and education initiatives, all of which are designed to benefit patient care. You can feel good knowing that 100% of your donation is directly allocated to research.